Melatonin

Melatonin yog indole-amine chav kawm me me-molecule biochemical compound, tsim los rau circadian-rhythm thiab cell-oxidative-stress laboratory tshawb fawb. Nws muaj tus yam ntxwv N-acetyl-methoxy indole-amine chemical skeleton, dav saws los npaj cov kev ntsuam xyuas cov kev daws teeb meem rau cell circadian-rhythm modulation in-vitro thwmsim.
Cov kws tshawb fawb siv cov khoom siv raw no rau kev tshawb nrhiav ntawm tes los tiv thaiv oxidative-txoj kev nyuaj siab, circadian-clock gene qhia kev teeb tsa, indole-amine derivative hloov kho kev tshawb fawb thiab biochemical intermediate validation.
Nyob rau hauv cov txheej txheem qhuav maub lab kev ua haujlwm, cov hmoov no siab-purity tuav ruaj khov indole-amine molecular skeleton. Nws ua kom ntseeg tau qhov kev ua tau zoo ntawm kev sib xyaw ua ke hauv aqueous-organic lab daws ib puag ncig, muab cov khoom siv txhim khu kev qha rau circadian cell qauv kuaj. Nws haum zoo kawg nkaus rau indole-amine biochemical formulation pre-study thiab tryptamine-derivative hluavtaws tshawb.

◆ Circadian-Clock Cell In-vitro Modulation Assay
Kev ua haujlwm raws li indole-amine biochemical additive rau cell incubation systems, pab soj ntsuam circadian-clock gene qhia variation nyob rau hauv atherosclerosis ntawm cell in-vitro tests.

◆ Indole-Amine Oxidative-Stress Comparative Reference
Ua raws li cov tshuaj tiv thaiv oxidative siv los kuaj cov molecule oxidation-degradation cov lus teb nyob rau hauv txawv lub teeb / oxygen raug nyob rau hauv cell-free lab tshuaj systems.

◆ Indole-Tryptamine Scaffold Synthetic Building-Block
Muab N-acetyl methoxy-substituted indole-amine skeleton rau organic lab synthesis, txhawb tryptamine-chav kawm derivative chemical transformation kev tshawb fawb.

◆ Mixed Aqueous-organic Medium Dissolution Compatibility
Soluble hauv ethanol / DMSO, ib nrab solubility hauv dej kub; tuaj yeem diluted mus rau hauv kab lis kev cai nruab nrab ntawm tes los npaj circadian-rhythm cell ua haujlwm kev tshuaj ntsuam xyuas.