Product Description
Repotrectinib yog ib qho hluavtaws me me molecule tyrosine kinase inhibitor compound, tshwj xeeb uas tsim los rau hauv -vitro oncology pharmacology mechanism tshawb fawb. Nws muaj tus yam ntxwv fused heterocyclic sequence qauv nta, dav saws los npaj hauv - vitro xeem cov kev daws teeb meem rau ROS1 thiab NTRK kinase ntsig txog cov qauv kev sim ntawm tes. Cov kws tshawb fawb siv cov khoom siv raw no rau kinase receptor binding mechanism kev tshawb nrhiav, qog cell proliferation inhibition cell qauv teeb, kev ntsuas kev ruaj ntseg thiab cov tshuaj siv tshuaj nruab nrab qhov ua tau zoo.
Raws li tus qauv kuaj mob khaub thuas- khaws cia kev ua haujlwm, qhov siab - purity crystalline hmoov muab kev ua haujlwm ruaj khov tom qab rov tsim dua. Nws tuav cov khoom siv tshuaj lom neeg ruaj khov hauv kev npaj DMSO aqueous test solution systems, muab cov ntaub ntawv siv tau zoo rau hauv -vitro kinase binding simulation thiab compound degradation research. Nws haum zoo kawg nkaus rau lub hom phiaj tshuaj tsim ua ntej- kev tshawb fawb thiab kev tshawb fawb me me ntawm cov tshuaj molecular.
COA
| Cov khoom | Specifications |
|---|---|
| Qhov tshwm sim | Dawb hmoov |
| Poob rau ziab | Tsawg dua lossis sib npaug li 2.0% |
| Residue ntawm Ignition | Ntau dua lossis sib npaug li 0.5% |
| Coj | Tsawg dua lossis sib npaug li 1 ppm |
| Arsenic | Tsawg dua lossis sib npaug li 1 ppm |
| Cadmium | Tsawg dua lossis sib npaug li 1 ppm |
| Mercury | Tsawg dua lossis sib npaug li 0.1 ppm |
| Total Aerobic suav | Tsawg dua lossis sib npaug li 1000 CFU / g |
| Poov & Pwm | Tsawg dua lossis sib npaug li 100 CFU / g |
| E.Coli, Salmonella | Tsis zoo |
| Txee lub neej | 24 lub hlis (sau thiab khaws cia deb ntawm lub teeb) |
Functions thiab Effects
◆ ROS1 / NTRK Kinase Inhibition Hauv -vitro Kev Tshawb Fawb
Kev ua haujlwm xws li hauv -vitro pharmacological additive rau cell incubation systems, simulates tyrosine kinase receptor inhibition effect thaum lub sij hawm oncology ntsig txog kev kuaj tshuaj tshuaj.
◆ Kev Ntsuas Me Me Molecule Kinase Inhibitor Hydrolysis Stability
Ua raws li tus qauv siv cov khoom siv los soj ntsuam cov molecular hydrolysis thiab oxidative degradation cov lus teb raws li pH sib txawv, qhov kub thiab txias hauv cell -cov kua tshuaj tiv thaiv dawb.
◆ Targeted Drug Heterocyclic Scaffold Building-Block
Muab cov active heterocyclic uas muaj cov pob txha mos molecular rau kev kuaj cov organic synthesis, txhawb kev tshawb nrhiav derivative molecule structural modification.
◆ DMSO Buffer Reconstitution Matching Performance
Yooj yim rau yaj hauv DMSO nruab nrab, tuaj yeem sib xyaw nrog physiological simulation ntsev los npaj ntau- cov khoom hauv - vitro qog cell pharmacological kev daws teeb meem.
Daim ntawv thov teb
◆ Hauv - vitro Tumor Targeted Pharmacology Mechanism Research
Lab- nplai siv reagent rau kev npaj cov cell incubation ua hauj lwm daws siv nyob rau hauv kinase inhibitor pharmacological tshuaj ntsuam xyuas, txhawb rov qab tshuaj formula tshuaj ntsuam rau lub hom phiaj anti- qog tshuaj tshawb fawb workflows.
◆ Targeted Anti-mob qog tshuaj Formulation Pre-Study
Siv nyob rau hauv lab-scale formulation txoj kev loj hlob ntawm lub qhov ncauj npaj npaj, ua raws li active raw khoom rau kev tshawb fawb tshiab me me molecule qhov ncauj xa rov qab.
◆ Me Me Molecule Drug Impurity & Analytical Method Validation
Siab -purity reference standard for drug impurity detection verification, thermal stability comparison test validation and pharmaceutical me molecule solution benchmark test.
Kev lag luam Scope
Ntim Thiab Kev Thauj Mus Los
Cov ntawv pov thawj
FAQ
Peb qhov chaw nyob
Tsis yog. 56, Jinye 1st Road, Hi-Tech Zone, Xi'an, xeev Shaanxi, Suav teb
Xov tooj
18192393517
E -mail
dennis04@xaltbio.com
Cim npe nrov: Tuam Tshoj repotrectinib manufacturers, lwm tus neeg, Hoobkas
