Rapamycin zog

Rapamycin zog
Paub meej
Khoom npe: Rapamycin zog
Lwm Lub Npe: Sirolimus, Rapamycin nyoos hmoov, mTOR inhibitor tshawb fawb reagent
Specification: Purity Ntau dua lossis sib npaug li 99%, Kev Tshawb Fawb Qib, HPLC kuaj, kev cai particle loj muaj
CAS Nr .: 53123-88-9
Cov tsos mob: Dawb rau tawm -dawb crystalline hmoov, soluble hauv DMSO, methanol thiab ethanol, tsis yooj yim soluble hauv dej, ruaj khov nyob rau hauv txias kaw cia txias
Cov txiaj ntsig tseem ceeb: Microbial fermentation qhov chaw ua raws li qis -kub recrystallization refining workflow, tsis tshua muaj hlau hnyav thiab cov ntsiab lus hnyav residual, uniform crystal morphology; Tsawg degradation impurities, ruaj khov solubility hauv cov kuab tshuaj organic, zoo -matched rau hauv - vitro mTOR cell signaling txoj kev tshawb fawb, sib xws nrog polar organic lab kuab tshuaj.
Kev Pabcuam Kev Pabcuam: Cov qauv sim me me hauv Tshuag, tus qauv lossis txias - kev xaiv xa khoom xa tuaj, kev cai ntim khoom tshwj xeeb muaj, tag nrho cov ntaub ntawv COA & MSDS, kev tshaj lij cell biology lab kev sib tham txog kev txhawb nqa.
Kev faib tawm yam khoom
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Product Description

 

Rapamycin yog ib qho ntuj macrolide me me -molecule compound, tsim tshwj xeeb rau hauv - vitro cell biology laboratory mechanism research. Nws muaj cov yam ntxwv ntawm cov tshuaj macrocyclic lactone, dav siv los npaj hauv - vitro test stock solutions for mTOR signal pathway related cell model tests. Cov kws tshawb fawb siv cov khoom siv raw no rau kev tshawb nrhiav kinase inhibition mechanism, cell autophagy qauv teeb, compound dose- teb kev soj ntsuam thiab tshuaj tiv thaiv -proliferation intermediate validation.
Nyob rau hauv cov txheej txheem lab txias- khaws cia kev ua haujlwm, qhov siab - purity crystalline hmoov muab kev ua haujlwm ruaj khov hauv cov kuab tshuaj organic. Nws tuav cov khoom siv tshuaj ruaj khov hauv kev npaj DMSO cov txheej txheem kev daws teeb meem, muab cov khoom siv raw cov ntaub ntawv txhim khu kev qha rau hauv - vitro cell voj voog kev tswj simulation thiab lactone- kev tshawb fawb tshuaj degradation. Nws haum zoo kawg nkaus rau cov tshuaj antitumor formulation ua ntej- kawm thiab macrolide- hom tshuaj molecular hloov kev tshawb nrhiav.

product-1297-1280

COA

 

 

Cov khoom Specifications
Qhov tshwm sim Dawb hmoov
Poob rau ziab Tsawg dua lossis sib npaug li 1.0%
Residue ntawm Ignition Ntau dua lossis sib npaug li 0.1%
Coj Tsawg dua lossis sib npaug li 2 ppm
Arsenic Tsawg dua lossis sib npaug li 1 ppm
Cadmium Tsawg dua lossis sib npaug li 1 ppm
Mercury Tsawg dua lossis sib npaug li 0.1 ppm
Total Aerobic suav Tsawg dua lossis sib npaug li 1000 CFU / g
Poov & Pwm Tsawg dua lossis sib npaug li 100 CFU / g
E.Coli, Salmonella Tsis zoo
Txee lub neej 24 lub hlis (sau thiab khaws cia deb ntawm lub teeb)

 

Functions thiab Effects

 

 

◆ mTOR Kinase Pathway Hauv -vitro Inhibition Research
Kev ua haujlwm xws li hauv -vitro pharmacological additive rau cell incubation systems, simulates lub hom phiaj mTOR kinase inhibition nyhuv thaum lub sij hawm cell autophagy pharmacological xeem.


◆ Organic-Phase Lactone Hydrolysis Stability Evaluation
Ua raws li tus qauv macrolide siv tshuaj los soj ntsuam cov lus teb ntawm molecular degradation nyob rau hauv ntau qhov kub thiab txias, hnyav hauv cell -dawb cov tshuaj tiv thaiv kab mob.


◆ Macrocyclic Lactone Pharmaceutical Scaffold Building-Block
Muab cov nquag macrolactone uas muaj cov pob txha mos molecular rau kev kuaj tshuaj organic synthesis, txhawb kev tshawb nrhiav kev hloov pauv molecular.


◆ Organic -Solvent Solubility Matching Performance
Yooj yim rau yaj hauv DMSO thiab luv luv -chain cawv nruab nrab, tuaj yeem sib xyaw nrog kab lis kev cai nruab nrab los npaj ntau- cov khoom hauv - vitro cell pharmacological kev daws teeb meem.

product-1280-1659

 

 

Daim ntawv thov teb

product-1358-1280

 

 

◆ Hauv -vitro Cell Autophagy & Signal Pathway Pharmacology Research
Lab- nplai siv reagent rau kev npaj cell incubation ua hauj lwm cov kev daws teeb meem siv nyob rau hauv mTOR pathway pharmacological tshuaj ntsuam xyuas, txhawb rov qab tshuaj formula tshuaj ntsuam xyuas cell biology tshuaj tshawb fawb workflows.


◆ Pharmaceutical Macrolide-Derivative Intermediate Exploration
Siv nyob rau hauv lab- nplai synthesis ntawm macrolactone uas muaj derivative tshuaj, ua raws li lub tsev tseem ceeb- thaiv kev tshawb nrhiav tshiab macrolide-chav kawm tshuaj molecular qaum.


◆ Siab -thov los ntawm Cell Compound Screening & Reference Calibration
Siab -purity reference standard for kinase inhibitor screening verification, thermal-stability comparison test validation and cell assay benchmark testing.

 

 

Kev lag luam Scope

 

 

0421001

 

Ntim Thiab Kev Thauj Mus Los

 

 

001

 

Cov ntawv pov thawj

 

 

222

 

FAQ

 

 

Q1: Lub luag haujlwm tseem ceeb dab tsi - cov xwm txheej ua haujlwm yog Rapamycin fais fab feem ntau siv rau?
A:Nws yog dav siv nyob rau hauv -vitro mTOR cell signaling kev tshawb fawb, macrolide compound stability testing thiab anti-cov tshuaj proliferation siab- los ntawm kev tshuaj ntsuam.
Q2: Nws lub npe CAS yog dab tsi?
CAS Nr .: 53123-88-9
 
Q3: Koj puas txhawb kev cai particle mesh loj dua li cov qauv Kev Tshawb Fawb Qib Siab dua lossis sib npaug li 99%?
A: Yog, ob qho tib si particle mesh thiab purity qib tuaj yeem hloov kho raws li koj qhov kev sim ntawm tes.
 
Q4: Rapamycin hmoov puas tuaj yeem thov ncaj qha rau tib neeg kev kho mob?
A: Cov khoom no yog nruj me ntsis rau kev soj ntsuam kuaj siv nkaus xwb, tsis yog rau tib neeg lossis tsiaj chaw kho mob / tshuaj lub hom phiaj.
Q5: Dab tsi yog qhov kev cia siab rau Rapamycin nyoos hmoov?
A: Thov khaws cia hauv qab -20 degree, qhuav, kaw, tsis txhob raug kub mus ntev los tiv thaiv macrolactone qauv hydrolysis degradation.
Q6: Yuav ua li cas txog nws qhov sib txawv ntawm cov dej thiab cov kuab tshuaj organic?
A: Insoluble hauv dej huv, dawb do soluble hauv DMSO thiab methanol; soluble tsis zoo nyob rau hauv alkane non{0}}polar organic solvents.
Q7: Puas yog batch-rau-batch impurity txawv cuam tshuam rau kuv cell autophagy incubation test?
A: Peb tswj hwm cov khoom muaj feem xyuam nrog- cov khoom ntawm qis- txheej txheem recrystallization kub; txhua pawg muab cov ntaub ntawv xeem impurity tag nrho rau koj lub xov tooj ntawm tes - kev soj ntsuam kev pheej hmoo.
Q8: Koj puas tuaj yeem muab cov tshuaj me me mg- theem sim kom muaj nuj nqis rau kev kuaj tshuaj ua ntej?
A: Yog lawm, cov qauv sim ntim me me muaj nyob rau koj qhov kev kuaj kab mob ua ntej ntawm tes.
 
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Peb qhov chaw nyob

Tsis yog. 56, Jinye 1st Road, Hi-Tech Zone, Xi'an, xeev Shaanxi, Suav teb

Xov tooj

18192393517

E -mail

dennis04@xaltbio.com

 

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